Our new Apparent+ tissue clearing approach is the one process that delipidates samples with no modify in morphology and with minimal influence on structural integrity.
Our switch-important SmartBatch+ procedure combines electrophoretic tissue clearing and immunolabeling into one significant-throughput machine.
Antibodies may possibly take weeks to diffuse by way of only a few millimeters of tissue, by using a steep labeling gradient from surface to Main.
Running the CLI straight from a Gradle endeavor just isn't at this time supported. A distribution has to be established through gradlew :j2d-cli:distZip to produce a zip file containing almost everything required to run.
SE makes use of a rotational electric powered field to disperse very electromobile molecules (for instance antibodies or surfactant micelles) throughout a porous sample with out detrimental electrically billed structures throughout the tissue. This allows 2-4 working day clearing of intact organs,
Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them fully transparent. This enables light penetration in to the sample and assures megatomi.com the acquisition of substantial-resolution, in-concentration graphic details.
Megatome is usually a novel microtome that enables for prime-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue problems and data reduction.
It’s time for you to up grade your microtome to Megatome. With accurate high-frequency slicing for an unmatched choice of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous apps.
Absolutely delipidate complete mouse brains or comparably sized samples in just one day with SmartBatch+, or in a single week with our passive clearing package.
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SHIELD avoids the variability of hydrogel embedding and the information decline from PFA preservation, shielding specimens for several rounds of processing.
Leverage the Apparent+ tissue clearing method, together with eFLASH and patented stochastic electrotransport technologies, to quickly crystal clear and label complete organs. Critical highlights and attributes involve:
Our novel SHIELD tissue preservation system varieties intramolecular bonds utilizing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.